张滕（Teng Zhang），研究员，博士生导师        

学科：动物生殖生物学及生物技术

研究方向:：生殖生物学、表观遗传学、生物信息学

电话：0471-4995002

邮箱：zhangteng428@163.com

通讯地址：内蒙古呼和浩特市昭君路24号，tyc1286太阳成集团（南校区）44118太阳成城集团，邮编010000

简要介绍：

张滕，医学博士，tyc1286太阳成集团“骏马计划”高层次人才入选者，省部共建草原家畜生殖调控与繁育国家重点实验室生殖发育与代谢调控研究组PI，内蒙古自治区“草原英才”获得者，Front Cell Dev Biol、Environment Res、Gene、Peer J等期刊审稿专家。主要从事哺乳动物配子发生和早期胚胎发育的代谢稳态和表观修饰的机理研究，尤其关注于哺乳动物卵泡发生与发育、卵子成熟和早期胚胎发育等研究领域。在Gut、PNAS、J Pineal Res、Development、Biol Reprod 等国际知名期刊上发表论文20余篇。

Publications：

1. Zhang, Teng#*; Sun, Peng#; Geng, Qi; Fan, Haitao; Gong, Yutian; Hu, Yanting; Shan, Liying; Sun, Yuanchao; Shen, Wei; Zhou, Yang*; Disrupted spermatogenesis in a metabolic syndrome model: the role of vitamin A metabolism in the gut– testis axis, Gut, 2021, 0: 1-10. doi:10.1136/gutjnl-2020-323347. (医学一区，2019 IF=19.819，共同通讯)

2. Liu JC, Li L, Yan HC, Zhang T, Zhang P, Sun ZY, De Felici M, Reiter RJ, Shen W. Identification of Oxidative Stress-Related Xdh Gene as a di(2-ethylhexyl)phthalate (DEHP) Target and the Use of Melatonin to Alleviate the DEHP-induced Impairments in Newborn Mouse Ovaries. J Pineal Res. 2019 Aug; 67(1): e12577. (医学一区，2018IF=15.221)

3. Guo J^#, Zhang T^#, Guo YS, Sun T, Li H, Zhang XY, Yin H, Cao GY, Yin YX, Wang H, Shi LY, Guo XJ, Sha JH, Eppig J, Su YQ. Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice. Proc Natl Acad Sci U S A. 2018 Jun 5; 115(23): E5326-E5333. (^#, co-first author). (综合性一区，2018IF=9.581)

4. Zhang T, Zhou Y, Li L, Zhao Y, De Felici M, Reiter RJ, Shen W. Melatonin protects prepuberal testis from deleterious effects of BPA and DEHP by preserving H3K9 methylation. J Pineal Res. 2018 Sep; 65(2): e12497. (医学一区，2018IF=15.221)

5. Zhang T, Zhou Y, Li L, Wang ZB, Shen W, Schatten H, Sun QY. CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes. Development. 2017 Jan 15;144(2):305-312. (生物学二区，2018IF=5.763)

6. Zhang T, Zhou Y, Li L, Wang HH, Ma XS, Qian WP, Shen W, Schatten H, Sun QY. SIRT1, 2, 3 protect mouse oocytes from postovulatory aging. Aging (Albany NY). 2016 Apr;8(4):685-96. (医学二区，2018IF=5.515)

7. Zhang T, Shen W, De Felici M, Zhang XF. Di (2-ethylhexyl) phthalate: adverse effects on folliculogenesis that cannot be neglected. Environ Mol Mutagen. 2016 Oct;57(8):579-588.（环境科学与生态学三区，2018IF=2.528）

8. Zhang T, Zhou Y, Qi ST, Wang ZB, Qian WP, Ouyang YC, Shen W, Schatten H, Sun QY. Nuf2 is required for chromosome segregation during mouse oocyte meiotic maturation. Cell Cycle. 2015;14(16):2701-10. (生物学三区，2018IF=3.259)

9. Zhang T, Li L, Qin XS, Zhou Y, Zhang XF, Wang LQ, Massimo De Felici, Chen H, Qin GQ, Shen W. Di-(2-ethylhexyl) Phthalate and Bisphenol A exposure impairs mouse primordial follicle assembly in vitro. Environ Mol Mutagen. 2014 May;55(4):343-53. 环境科学与生态学三区，2018IF=2.528）

10. Zhang JH^#, Zhang T^#, Gao SH, Wang K, Yang XY, Mo FF, Na Yu, An T, Li YF, Hu JW, Jiang GJ. Mitofusin-2 is required for mouse oocyte meiotic maturation. Sci Rep. 2016 Aug 3;6:30970. (^#, co-first author). (综合性三区，2018IF=4.011)

11. Jiang GJ^#, Zhang T^#, An T, Zhao DD, Yang XY, Zhang DW, Zhang Y, Mu QQ, Yu N, Ma XS, Gao SH. Differential expression of long noncoding RNAs between sperm samples from diabetic and non-diabetic mice. PLoS One. 2016 Apr 27;11(4):e0154028. (^#, co-first author). (综合性三区，2018IF=2.776)

12. Zhang RQ, Wang JJ, Zhang T, Zhai HL, Shen W. Copy-number variation in goat genome sequence: A comparative analysis of the different litter size trait groups. Gene. 2019 May 15;696:40-46. (生物学三区，2018IF=2.638)

13. Wang HH, Cui Q, Zhang T, Guo L, Dong MZ, Hou Y, Wang ZB, Shen W, Ma JY, Sun QY. Removal of mouse ovary fat pad affects sex hormones, folliculogenesis and fertility. Journal of J Endocrinol. 2017 Feb;232(2):155-164. (医学二区，2018IF=4.381)

14. Wang HH, Cui Q, Zhang T, Wang ZB, Ouyang YC, Shen W, Ma JY, Schatten H, Sun QY. Rab3A, Rab27A, and Rab35 regulate different events during mouse oocyte meiotic maturation and activation. Histochem Cell Biol. 2016 Jun;145(6):647-57. (生物学四区，2018IF=2.640)

15. Guo L, Wang ZB, Wang HH, Zhang T, Qi ST, Ouyang YC, Hou Y, Sun QY. Nek11 regulates asymmetric cell division during mouse oocyte meiotic maturation. Biochem Biophys Res Commun. 2016 Jun 10;474(4):667-672. (生物学三区，2018IF=2.705)

16. Yi ZY, Ma XS, Liang QX, Zhang T, Xu ZY, Meng TG, Ouyang YC, Hou Y, Schatten H, Sun QY, Quan S. Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes. Sci Rep. 2016 Dec 19;6:38574. (综合性三区，2018IF=4.011)

17. Wei YC, Zhang T, Wang YP, Schatten H, Sun QY. Polar bodies in assisted reproductive technology: current progress and future perspectives. Biol Reprod. 2015 Jan;92(1):19. (生物学二区，2018IF=2.960)

18. Zhang XF, Zhang T, Han Z, Liu JC, Liu YP, Ma JY, Li L, Shen W. Transgenerational inheritance of ovarian development deficiency induced by maternal diethylhexyl phthalate exposure. Reprod Fertil Dev. 2015 Nov;27(8):1213-21. (生物学三区，2018IF=1.723)

19. Li L, Zhang T, Qin XS, Ge W, Ma HG, Sun LL, Hou ZM, Chen H, Chen P, Qin GQ, Shen W, Zhang XF. Exposure to diethylhexyl phthalate (DEHP) results in a heritable modification of imprint genes DNA methylation in mouse oocytes. Mol Biol Rep. 2014 Mar;41(3):1227-35. (生物学四区，2018IF=2.107)

20. Ma JY, Zhang T, Shen W, Schatten H, Sun QY. Molecules and mechanisms controlling the active DNA demethylation of the mammalian zygotic genome. Protein Cell. 2014 Nov;5(11):827-36. (生物学一区，2018IF=7.575)

21. Zhou Y, Zhang T, Zhang QK, Jiang Y, Xu DG, Zhang M, Shen W , Pan QJ. Unstable expression of transgene is associated with the methylation of CAG promoter in the offspring from the same litter of homozygous transgenic mice. Mol Biol Rep. 2014 Aug;41(8):5177-86. (生物学四区，2018IF=2.107)

22. Li L, Zhang T, Qin XS , Ge W, Ma HG , Sun LL, Hou ZM, Chen H, Qin GQ , Shen W , Zhang XF. Exposure to diethylhexyl phthalate (DEHP) results in a heritable modification of imprint genes DNA methylation in mouse oocytes. Mol Biol Rep. 2014 Mar;41(3):1227-35. (生物学四区，2018IF=2.107)

23. Zhang XF, Zhang T, Wang L, Zhang HY, Chen YD, Qin XS, Feng YM, Feng YN, Shen W, Li L. Effects of diethylhexyl phthalate (DEHP) given neonatally on spermatogenesis of mice. Mol Biol Rep. 2013 Nov;40(11):6509-17. (生物学四区，2018IF=2.107)