苏小虎,男,汉族,1986年出生,内蒙古农业大学博士,中山大学博士后。现任44118太阳成城集团助理研究员,硕士生导师。
电子邮箱:13947144670@139.com
研究方向:
利用转录组、蛋白质组、代谢组、基因组学等技术对家畜重要经济性状进行机制探讨及选育体系优化,利用基因编辑技术对牛羊进行性状改良提升,采用传统育种技术与现代生物育种技术进行新品种奶绵羊培育,繁殖生物技术优化。
学习和工作经历:
2004/09-2008/06,长春理工大学,44118太阳成城集团,生物技术,学士
2009/09-2012/06,内蒙古农业大学,44118太阳成城集团,发育生物学,硕士
2012/09-2016/12,内蒙古农业大学,44118太阳成城集团,发育生物学,博士
2017/01-2017/06,tyc1286太阳成集团,44118太阳成城集团,研究助理
2017/07-2020/05,中山大学,44118太阳成城集团,博士后
2020/06-至今,tyc1286太阳成集团,44118太阳成城集团,助理研究员
主持及参与项目:
1. 国家自然科学基金,32160768,SCGB2A2在绵羊乳成分形成中的作用及机制研究,2022/01-2025.12,35万元,主持
2. 内蒙古自治区科技计划项目,2021GG0287,应用分子标记辅助选择和高效繁殖技术培育肉乳兼用绵羊新品种,2021/01-2023/12,60万元,子课题负责人
3. tyc1286太阳成集团国重自主课题,2021ZZ0203,绵羊基因组编辑技术优化与高免疫力奶绵羊模型的建立,2021/01-2023/12,40万元,主持
部分发表论文:
1. Su X, Zheng Z, Zhang L, Bai U, Ma Y, Dou Y, Zhang X, Su G, Zhou N, Li G, and Zhang L (2021) Proteomic profiling of ovine milk after grading up. J Dairy Res 88, 201-204.(三区)
2. Bai U#, Su X#, Zheng Z, Zhang L, Ma Y, Dou Y, Zhang X, Su G, Li G, and Zhang L (2021) Comparative metabolomics analysis of Small‑Tailed Han and DairyMeade ovine milk. European Food Research and Technology 247, 2869–2876. (三区)
3. Bai U#, Su X#, Zheng Z, Zhang L, Ma Y, Dou Y, Zhang X, Su G, Zhou N, Li G, and Zhang L (2021) Comparative whey proteome analysis of small-tailed Han and DairyMeade ovine milk. J Dairy Res 88, 420-424.(三区)
4. Su X, Wang S, Gao G, Zhou X, Han L, Su G, Zhang J, Bai W, Wang X, Li G, and Zhang L (2020) Comparative analysis of bovine maternal corpus luteum microRNAs with aberrant and normal developed cloned fetus at late gestation. Genes Genomics 42, 283-290.(四区)
5. Su X, Chen W, Cai Q, Liang P, Chen Y, Cong P, and Huang J (2020) Effective generation of maternal genome point mutated porcine embryos by injection of cytosine base editor into germinal vesicle oocytes. Sci China Life Sci 63, 996-1005.(一区top)
6. Su X, Chen W, Cai Q, Liang P, Chen Y, Cong P, and Huang J (2019) Production of non-mosaic genome edited porcine embryos by injection of CRISPR/Cas9 into germinal vesicle oocytes. J Genet Genomics 46, 335-342.(二区)
7. Su X, Gao G, Wang S, Su G, Zheng Z, Zhang J, Han L, Ling Y, Wang X, Li G, and Zhang L (2019) CircRNA expression profile of bovine placentas in late gestation with aberrant SCNT fetus. J Clin Lab Anal 33, e22918.(四区)
8. Gao G, Wang S, Zhang J, Su G, Zheng Z, Bai C, Yang L, Wei Z, Wang X, Liu X, Guo Z, Li G*, Su X*, and Zhang L* (2019) Transcriptome-wide analysis of the SCNT bovine abnormal placenta during mid- to late gestation. Sci Rep 9, 20035.(三区)
9. Su X, Wang S, Su G, Zheng Z, Zhang J, Ma Y, Liu Z, Zhou H, Zhang Y, and Zhang L (2018) Production of microhomologous-mediated site-specific integrated LacS gene cow using TALENs. Theriogenology 119, 282-288.(二区)
10. Su X, Ling Y, Liu C, Meng F, Cao J, Zhang L, Zhou H, Liu Z, and Zhang Y (2015) Isolation, Culture, Differentiation, and Nuclear Reprogramming of Mongolian Sheep Fetal Bone Marrow-Derived Mesenchymal Stem Cells. Cell Reprogram 17, 288-296.(四区)
授权发明专利:
1. 一种非嵌合基因编辑猪胚胎模型的构建方法,ZL 201910616058.1
2. 一种奶绵羊精液冷冻保存方法及其稀释液,202110174106.3